SS-31 – 10 mg

SS-31 is a synthetic peptide derived from a truncated form of the natural compound BPC-157. Originally studied for its potential therapeutic effects on muscle and tissue repair, SS-31 has garnered interest in academic research due to its ability to modulate cellular processes associated with oxidative stress and inflammation. This peptide is categorized under acyl-CoA desaturase inhibitors, demonstrating potential utility in studying metabolic pathways and cardiovascular health. The 10 mg dose provided in this research-grade formulation is intended for use in laboratory settings for experimental purposes only.

Research Context

SS-31 was first synthesized in the 1990s and has since been extensively investigated in preclinical studies. Its mechanisms of action include the inhibition of pro-inflammatory signaling pathways, enhancement of endothelial function, and modulation of cellular stress responses. While initial research focused on wound healing and tissue regeneration, subsequent studies have expanded its potential applications in cardiovascular biology, metabolic health, and aging-related research. The peptide’s structure—comprising a cyclic backbone with an N-terminal acetyl group—contributes to its stability and bioavailability when administered in research models.

Research Overview

SS-31 has been evaluated in a range of experimental models, including murine and porcine studies, to assess its effects on:

• cardiac and vascular remodeling post-injury
• muscle atrophy and regeneration
• neuroprotection in ischemic conditions
• oxidative stress response in metabolic diseases

The peptide’s ability to suppress pro-inflammatory cytokines such as TNF-α and IL-6 has been particularly notable, suggesting potential utility in chronic disease models. Early studies also indicated improvements in mitochondrial function and endothelial dysfunction following exposure to SS-31, though these findings remain largely exploratory in the context of human health applications.

Key Research Focus Areas

• Cardiovascular Biology: Investigation of SS-31’s role in reducing atherosclerosis, improving endothelial function, and mitigating myocardial infarction outcomes in animal models.
• Metabolic Health: Exploration of its effects on insulin sensitivity, lipid metabolism, and obesity-related inflammation through studies in high-fat diet-induced models.
• Musculoskeletal Repair: Examination of its efficacy in accelerating tendon, ligament, and skeletal muscle repair in experimental trauma or disease settings.
• Neurodegeneration: Preliminary studies assessing neuroprotective effects in models of stroke, traumatic brain injury, or neurodegenerative diseases.
• Aging Research: Investigation of its potential anti-aging mechanisms, including modulation of senescence-associated secretory phenotypes (SASP) and cellular senescence.

Important Research Use Only Statement

This product is intended solely for academic, industrial, or laboratory research purposes. The chemical SS-31 (and its derivatives) has not been evaluated for safety in human or animal consumption. Research institutions and researchers must comply with all applicable local, national, and international regulations regarding the handling, storage, and use of research chemicals. Proper safety protocols, including hazard assessments and risk management, must be followed at all times.

For research use only. Not for human or animal consumption.